Critical Limb Ischemia: Diagnosis and Current Management

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Management of Critical Limb Ischemia.

Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue loss, such as nonhealing ulcers or gangrene, related to peripheral artery disease. CLI has a high short-term risk of limb loss and cardiovascular events. Noninvasive or invasive angiography help determine the feasibility and approach to arterial revascularization. An endovascular-first approach is often advoc...

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Critical Limb Ischemia: Current Trends and Future Directions

C ritical limb ischemia (CLI), which is at the end of the peripheral artery disease (PAD) spectrum, is associated with excessively high risk for cardiovascular events, including myocardial infarction, and death. Mortality rates as high as 20% within 6 months from diagnosis and exceeding 50% at 5 years have been reported for CLI, whereas 1-year mortality rates in nonrevascularizable, so-called n...

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[Critical limb ischemia].

Chronic critical limb ischemia is defined as ischemia which generally endangers the distal part of a limb. If the ischemia is unrelenting, there is a high risk that amputation will be required. These critical limbs were amputated as an initial treatment long ago. Now it becomes clear that disabling patients have very poor quality of life after major amputation, and ischemic leg produces noxious...

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BACKGROUND Some 40 000 lower limb amputations are performed in Germany each year, 70% of them in diabetics. About 80% of all major amputations may be preventable with the use of new interventional and vascular surgical procedures, particularly on the arteries of the leg and foot. We present the current state of the art in revascularization techniques and evaluate their usefulness for preservati...

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Critical Limb Ischemia

Critical limb ischemia (CLI), defined as chronic ischemic rest pain, ulcers, or gangrene attributable to objectively proven arterial occlusive disease, is the most advanced form of peripheral arterial disease. Traditionally, open surgical bypass was the only effective treatment strategy for limb revascularization in this patient population. However, during the past decade, the introduction and ...

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ژورنال

عنوان ژورنال: Journal of the Minneapolis Heart Institute Foundation

سال: 2017

ISSN: 2475-0190,2475-0204

DOI: 10.21925/mplsheartjournal-d-17-00004